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Schedule of Accrued Liabilities Schedule of Accrued Liabilities [Table Text Block] Cash and Cash Equivalents [Domain] Cash and Cash Equivalents [Domain] Equity [Abstract] Equity [Abstract] Entity Tax Identification Number Entity Tax Identification Number Maximum number of shares provided for issuance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized Capitalized Contract Cost [Table] Capitalized Contract Cost [Table] Purchase commitments to be paid Purchase Obligation, to be Paid, Remainder of Fiscal Year Weighted Average Remaining Contractual Term, Options exercisable Share-Based Payment Arrangement, Option, Exercise Price Range, Exercisable, Weighted Average Remaining Contractual Term Payment received from license agreement Proceeds from License Fees Received Revenue from Contract with Customer [Abstract] Revenue from Contract with Customer [Abstract] Net decrease in cash, cash equivalents and restricted cash Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Commercial paper Commercial Paper [Member] Entity Central Index Key Entity Central Index Key Antidilutive Securities, Name Antidilutive Securities, Name [Domain] Interest income Investment Income, Interest Measurement Frequency Measurement Frequency [Axis] Research and Development Research and Development Expense, Policy [Policy Text Block] Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Concentration of Credit Risk Concentration Risk, Credit Risk, Policy [Policy Text Block] Accrued other Other Accrued Liabilities, Current Entity [Domain] Entity [Domain] City Area Code City Area Code Accrued professional fees Accrued Professional Fees, Current Assets Assets [Abstract] Impairment of acquired contract intangible asset Impairment of Intangible Assets (Excluding Goodwill) Statement of Stockholders' Equity [Abstract] Statement of Stockholders' Equity [Abstract] Sale of Stock [Axis] Sale of Stock [Axis] Cash flows from financing activities: Net Cash Provided by (Used in) Financing Activities [Abstract] Capitalized Contract Cost [Line Items] Capitalized Contract Cost [Line Items] Net Loss per Share Attributable to Common Stockholders Earnings Per Share, Policy [Policy Text Block] Supplemental disclosure of non-cash activities: Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract] Share-based compensation expense Share-Based Payment Arrangement, Noncash Expense Weighted-average grant date fair value (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Warrants outstanding (in shares) Class of Warrant or Right, Outstanding Purchases of property and equipment Payments to Acquire Property, Plant, and Equipment Cowen and Company LLC Cowen and Company LLC [Member] Cowen and Company LLC Research and development Research and Development Expense [Member] Payments related to milestone Payments Related To Milestone Payments related to milestone. Accrued clinical Accrued Clinical Current Accrued clinical current. Customer [Domain] Customer [Domain]