0000001 - Document - Cover link:presentationLink link:calculationLink link:definitionLink 9952151 - Statement - Condensed Consolidated Balance Sheets link:presentationLink link:calculationLink link:definitionLink 9952152 - Statement - Condensed Consolidated Balance Sheets (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952153 - Statement - Condensed Consolidated Statements of Operations and Comprehensive Income (Loss) link:presentationLink link:calculationLink link:definitionLink 9952154 - Statement - Condensed Consolidated Statements of Stockholders' Equity link:presentationLink link:calculationLink link:definitionLink 9952155 - Statement - Condensed Consolidated Statements of Cash Flows link:presentationLink link:calculationLink link:definitionLink 9952156 - Disclosure - Nature of Organization and Operations link:presentationLink link:calculationLink link:definitionLink 9952157 - Disclosure - Summary of Significant Accounting Policies link:presentationLink link:calculationLink link:definitionLink 9952158 - Disclosure - Fair Value Measurement link:presentationLink link:calculationLink link:definitionLink 9952159 - Disclosure - Short-Term Investments and Cash Equivalents link:presentationLink link:calculationLink link:definitionLink 9952160 - Disclosure - Accrued Liabilities link:presentationLink link:calculationLink link:definitionLink 9952161 - Disclosure - Operating Lease link:presentationLink link:calculationLink link:definitionLink 9952162 - Disclosure - License Agreements link:presentationLink link:calculationLink link:definitionLink 9952163 - Disclosure - Stockholders' Equity link:presentationLink link:calculationLink link:definitionLink 9952164 - Disclosure - Share-Based Compensation link:presentationLink link:calculationLink link:definitionLink 9952165 - Disclosure - Employee Stock Purchase Plan link:presentationLink link:calculationLink link:definitionLink 9952166 - Disclosure - Income Taxes link:presentationLink link:calculationLink link:definitionLink 9952167 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 9952168 - Disclosure - Restructuring link:presentationLink link:calculationLink link:definitionLink 9952169 - Disclosure - Divestiture of FYARRO link:presentationLink link:calculationLink link:definitionLink 9952170 - Disclosure - Segment Information link:presentationLink link:calculationLink link:definitionLink 9955511 - Disclosure - Summary of Significant Accounting Policies (Policies) link:presentationLink link:calculationLink link:definitionLink 9955512 - Disclosure - Summary of Significant Accounting Policies (Tables) link:presentationLink link:calculationLink link:definitionLink 9955513 - Disclosure - Fair Value Measurement (Tables) link:presentationLink link:calculationLink link:definitionLink 9955514 - Disclosure - Short-Term Investments and Cash Equivalents (Tables) link:presentationLink link:calculationLink link:definitionLink 9955515 - Disclosure - Accrued Liabilities (Tables) link:presentationLink link:calculationLink link:definitionLink 9955516 - Disclosure - Operating Leases (Tables) link:presentationLink link:calculationLink link:definitionLink 9955517 - Disclosure - Share-Based Compensation (Tables) link:presentationLink link:calculationLink link:definitionLink 9955518 - Disclosure - Employee Stock Purchase Plan (Tables) link:presentationLink link:calculationLink link:definitionLink 9955519 - Disclosure - Divestiture of FYARRO (Tables) link:presentationLink link:calculationLink link:definitionLink 9955520 - Disclosure - Segment Information (Tables) link:presentationLink link:calculationLink link:definitionLink 9955521 - Disclosure - Nature of Organization and Operations - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955522 - Disclosure - Summary of Significant Accounting Policies - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955523 - Disclosure - Summary of Significant Accounting Policies - Schedule of Cash, Cash Equivalents and Restricted Cash (Details) link:presentationLink link:calculationLink link:definitionLink 9955524 - Disclosure - Summary of Significant Accounting Policies - Schedule of Inventory (Details) link:presentationLink link:calculationLink link:definitionLink 9955525 - Disclosure - Summary of Significant Accounting Policies - Schedule of Property and Equipment (Details) link:presentationLink link:calculationLink link:definitionLink 9955526 - Disclosure - Summary of Significant Accounting Policies - Schedule of Gross-to-Net Sales Adjustments (Details) link:presentationLink link:calculationLink link:definitionLink 9955527 - Disclosure - Summary of Significant Accounting Policies - Schedule of Earnings Per Share, Basic and Diluted (Details) link:presentationLink link:calculationLink link:definitionLink 9955528 - Disclosure - Fair Value Measurement (Details) link:presentationLink link:calculationLink link:definitionLink 9955529 - Disclosure - Short-Term Investments and Cash Equivalents (Details) link:presentationLink link:calculationLink link:definitionLink 9955530 - Disclosure - Accrued Liabilities - Schedule of Accrued Liabilities (Detail) link:presentationLink link:calculationLink link:definitionLink 9955531 - Disclosure - Operating Leases - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955532 - Disclosure - Operating Leases - Schedule of Information Related to Lease (Details) link:presentationLink link:calculationLink link:definitionLink 9955533 - Disclosure - Operating Leases - Schedule of Rent Expense and Cash Paid for Leases (Details) link:presentationLink link:calculationLink link:definitionLink 9955534 - Disclosure - License Agreements - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955535 - Disclosure - Stockholders' Equity - Narrative (Detail) link:presentationLink link:calculationLink link:definitionLink 9955536 - Disclosure - Share-Based Compensation - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955537 - Disclosure - Share-Based Compensation - Schedule of Stock Option Activity (Detail) link:presentationLink link:calculationLink link:definitionLink 9955538 - Disclosure - Share-Based Compensation - Schedule of Recognized Compensation Cost Restricted Stock Units (Details) link:presentationLink link:calculationLink link:definitionLink 9955539 - Disclosure - Share-Based Compensation - Schedule of Recognized Compensation Cost Related to Employee and Non-employee Stock-Based Compensation Activity (Detail) link:presentationLink link:calculationLink link:definitionLink 9955540 - Disclosure - Share-Based Compensation - Stock Options Valuation Assumptions (Detail) link:presentationLink link:calculationLink link:definitionLink 9955541 - Disclosure - Employee Stock Purchase Plan - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955542 - Disclosure - Employee Stock Purchase Plan - Calculation Assumptions (Details) link:presentationLink link:calculationLink link:definitionLink 9955543 - Disclosure - Income Taxes - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955544 - Disclosure - Commitments and Contingencies - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955545 - Disclosure - Restructuring (Details) link:presentationLink link:calculationLink link:definitionLink 9955546 - Disclosure - Divestiture of FYARRO - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955547 - Disclosure - Divestiture of FYARRO - Schedule of Net Assets Disposed (Details) link:presentationLink link:calculationLink link:definitionLink 9955548 - Disclosure - Segment Information - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955549 - Disclosure - Segment Information - Schedule of Segment Reporting Information, by Segment (Details) link:presentationLink link:calculationLink link:definitionLink